One of the Most Highly Trained Physicians in the Southeast
John W. Tyrone, M.D.
Dr. Tyrone has been published numerous times and has presented his work both nationally and internationally.
John W. Tyrone, M.D., is a board-certified plastic surgeon serving Gainesville, FL, and the North Central Florida region. Among his many accomplishments are more than a dozen publications featuring Dr. Tyrone’s research, writings, and presentations.
Plastic Surgeon Publications, Research & Writings
Dr. Tyrone has been published numerous times and stands as an authority on plastic surgery, plastic surgery recovery, and reconstructive plastic surgery.
Tyrone, J. W., Losken, A., & Hester, T. R. (2002). Nipple areola reconstruction. Breast disease, 16, 117–122.
Excerpt: “Creation of the nipple areolar complex often represents the final hurdle in a long and arduous reconstructive process for women with breast cancer. …”
Xia, Y. P., Zhao, Y., Tyrone, J. W., Chen, A., & Mustoe, T. A. (2001). Differential activation of migration by hypoxia in keratinocytes isolated from donors of increasing age: implication for chronic wounds in the elderly. The Journal of investigative dermatology, 116(1), 50–56.
Excerpt: “Chronic wound healing conditions are often observed in elderly patients with poor tissue oxygenation. Impaired re-epithelialization is a hallmark of these wounds, …”
Tyrone, J.W., Mogford, J.E., Chandler, L.A., Ma, C., Xia, Y., Pierce, G.F., & Thomas A. Mustoe, M.F. (2000). Collagen-embedded platelet-derived growth factor DNA plasmid promotes wound healing in a dermal ulcer model. The Journal of surgical research, 93 2, 230-6 .
Excerpt: “Gene therapy has shown limited efficacy for treating congenital diseases, partly due to temporary gene expression and host immune responses. …”
Tyrone, J.W., Marcus, J.R., Bonomo, S.R., Mogford, J.E., Xia, Y., & Thomas A. Mustoe, M.F. (2000). Transforming growth factor beta3 promotes fascial wound healing in a new animal model. Archives of surgery, 135 10, 1154-9 .Hypothesis: “Transforming growth factor beta(3) (TGF-beta(3)) promotes fascial wound healing in a new animal model, as measured by wound breaking strength, collagen deposition, and cellular proliferation.”
Marcus, J.R., Tyrone, J.W., Bonomo, S.R., Xia, Y., & Thomas A. Mustoe, M.F. (2000). Cellular Mechanisms for Diminished Scarring with Aging. Plastic and Reconstructive Surgery, 105, 1591–1599.
Excerpt: “The study of an age‐dependent spectrum of scar formation is driven by the desire to understand and recapitulate scarless healing. …”
Abstract Presentation: “Topical Platelet-Derived Growth Factor Gene Therapy Enhances Wound Healing”, University of California, Davis Surgical Forum, Sacramento, California, June 1999. UCD “Best Paper – UCD Residents’ Research Day Award”.
Abstract Presentation: “A Novel Gene Therapy Approach To Wound Healing: Topical Plasmid Platelet-Derived Growth Factor DNA Without A Viral Vector”, American College of Surgeon Surgical Forum Manual. Oct 1999
Abstract Presentation: “Neutralization of Transforming Growth Factor Beta Isoforms 1,2, and 3 Delays Wound Closure in Full-thickness Dermal Ulcers”, American College of Surgeon Surgical Forum. Oct 1999
Chao JD, Tyrone JW, Xia Y, Mustoe TA (Oct 1999). Neutralization of Transforming Growth Factor Beta Isoforms 1,2, and 3 Delays Wound Closure in Full-thickness Dermal Ulcers, American College of Surgeon Surgical Forum Manual.
Tyrone JW, Mustoe TA (1999). Chapter 1: The Principles of Wound Healing in Plastic Surgery Secrets, ed. J. Weinzweig, 1st Edition, Hanley & Belfus, Philadelphia.
Marcus, J.R., Tyrone, J.W., Few, J.W., Fine, N.A., & Thomas A. Mustoe, M.F. (1999). Optimization of conscious sedation in plastic surgery. Plastic and reconstructive surgery, 104 5, 1338-45 .Excerpt: “The administration of conscious sedation by the plastic surgeon must be safe, efficient, and consistent. In the proper setting, with trained staff and appropriate backup, conscious sedation can allow optimal patient satisfaction with expedient recovery in addition to cost containment. …”
Abstract Presentation: “Effects of Hyperbaric Oxygen, TGF-b3 and Combination Treatment on a New Chronic Wound Model”, Wound Healing Society, Salt Lake City, Utah, June 1998
Abstract Presentation: “TGF-β3 Improves Fascial Healing in a New Animal Model” University of California, Davis Surgical Forum, Oakland, California, June 1998
Abstract Presentation: “TGF-β3 Improves Fascial Healing in a New Animal Model”, European Tissue Repair Society, Copenhagen, Denmark, September 1998
Poster: “Computer Aided Histological Analysis: New Techniques” European Tissue Repair Society, Copenhagen, Denmark, September 1998
Abstract Presentation: Marcus, J.R., Tyrone, J.W., Few, J.W., Fine, N.A., & Thomas A. Mustoe, M.F. (1999). Optimization of conscious sedation in plastic surgery. Plastic and reconstructive surgery, 104 5, 1338-45 .
A Plastic Surgeon You Can Trust
Dr. Tyrone has been recognized, honored and awarded for his excellence in plastic surgery.
Stynchecomb Award for Outstanding Achievement In Plastic Surgery; 2004
Selected Chief-Administrative Resident in Plastic Surgery; 2003
Selected Chief-Administrative Resident in General Surgery; 2000
Plastic Surgery Education Foundation(PSEF) Research Grant; 1999
“Best Paper” – UCD Residents’ Research Day Award; 1999
Selected to Residency Advisory Committee; 1999
Elected “Outstanding Surgery Intern of the Year”; 1995
Honors Course in Surgery (by invitation); 1994
Omicron Delta Epsilon Honor Society; 1990
Dean’s List – University of Florida; 1988
Award for Excellence in Science; 1985
Certifications, Licensure & Examinations
Plastic Surgery In-Service Examination: 75th, 92nd Percentile
Board Certified in General Surgery by the American Board of Surgery
American Board of Surgery In-Service Examinations: 92nd, 85th, 88th, 78th, 81st Percentiles
Medical Licensing, Georgia #050454
Medical Licensing, Illinois #0036-096873
Medical Licensing, California #A060003
Advanced Trauma Life Support, Provider
Advanced Cardiac Life Support, Provider
USMLE Step I, II, III: Passed